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1: Actinomycosis
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Published:January 2023
"Actinomycosis", Red Book Atlas of Pediatric Infectious Diseases, Tina Q. Tan, MD, FAAP
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Actinomycosis results from pathogen introduction following a breakdown in mucocutaneous protective barriers. Spread within the host are, by direct invasion of adjacent tissues, typically forming sinus tracts that cross tissue planes. The most common species causing human disease is Actinomyces israelii.
There are 3 common anatomical sites of infection. Cervicofacial is most common, often occurring after tooth extraction, oral surgery, or other oral/facial trauma or even from carious teeth. Localized pain and induration may progress to cervical abscess and “woody hard” nodular lesions (“lumpy jaw”), which can develop draining sinus tracts, usually at the angle of the jaw or in...