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19: Blastomycosis
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Published:January 2023
"Blastomycosis", Red Book Atlas of Pediatric Infectious Diseases, Tina Q. Tan, MD, FAAP
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Infections can be acute, chronic, or fulminant but are asymptomatic in up to 50% of infected people. The most common clinical manifestation of blastomycosis in children is cough (often productive) accompanying pulmonary disease, with fever, chest pain, and nonspecific symptoms such as fatigue and myalgia. Rarely, patients may develop acute respiratory distress syndrome. Typical radiographic patterns include consolidation, patchy pneumonitis, a mass-like infiltrate, or nodules. Blastomycosis can be misdiagnosed as bacterial pneumonia, tuberculosis, sarcoidosis, or malignant neoplasm. Disseminated blastomycosis, which can occur in up to 25% of symptomatic cases, most commonly involves the skin and osteoarticular structures. Cutaneous manifestations can...