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Most Helicobacter pylori infections in children are believed to be asymptomatic. H pylori may cause chronic active gastritis and may result in duodenal and, to a lesser extent, gastric ulcers. Persistent infection with H pylori also increases risk for the development of gastric cancers including mucosal-associated lymphoid tissue (MALT) lymphoma and adenocarcinoma in adults; however, this is an infrequent complication in children. In children, acute H pylori infection can result in gastroduodenal inflammation that manifests as epigastric pain, nausea, vomiting, hematemesis, and guaiac-positive stools; these symptoms are usually self-limited. There is no clear association between infection and recurrent abdominal pain...

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