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166: Zika
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Published:January 2023
"Zika", Red Book Atlas of Pediatric Infectious Diseases, Tina Q. Tan, MD, FAAP
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Most Zika virus infections are asymptomatic. When infection is symptomatic, the clinical disease is usually mild, and symptoms last for a few days to a week. Commonly reported signs and symptoms include fever, pruritic maculopapular rash, arthralgia, and conjunctival hyperemia. Other findings include myalgia, headache, edema of the extremities, vomiting, retro-orbital pain, and lymphadenopathy. Clinical laboratory abnormalities are observed uncommonly in symptomatic patients but can include thrombocytopenia, leukopenia, and increased liver aminotransferase concentrations. Severe disease requiring hospitalization and deaths are rare. However, Guillain-Barré syndrome and rare reports of other neurological complications (eg, meningoencephalitis, myelitis, and uveitis) have been associated with...