Diabetic embryopathy is defined as congenital anomalies that are linked to maternal diabetes. The association between diabetes and fetal, neonatal, and long-term complications is well-established. These complications include organ or structural maldevelopment, fetal growth abnormalities, and learning/psychiatric comorbidities. Recent studies have elucidated the pathophysiology behind these conditions and outlined new management approaches. Caudal regression syndrome, also known as sacral agenesis, is a well-known but less described complication of maternal diabetes. The purpose of this review is to summarize existing research on common neonatal morbidities in infants of mothers with diabetes with a focus on caudal regression syndrome and its long-term associations.
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October 2022
Articles|
October 01 2022
Diabetic Embryopathies
Saivaroon Gajagowni, BS;
Saivaroon Gajagowni, BS
*University of Missouri School of Medicine, Columbia, MO
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Pooja Nair, BS;
Pooja Nair, BS
*University of Missouri School of Medicine, Columbia, MO
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Alka C. Bapat, MD;
Alka C. Bapat, MD
†Department of Obstetrics and Gynecology, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, NY
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Akshaya J. Vachharajani, MD
Akshaya J. Vachharajani, MD
‡Division of Neonatology, Department of Child Health, University of Missouri School of Medicine, Columbia, MO
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Neoreviews (2022) 23 (10): e677–e688.
Citation
Saivaroon Gajagowni, Pooja Nair, Alka C. Bapat, Akshaya J. Vachharajani; Diabetic Embryopathies. Neoreviews October 2022; 23 (10): e677–e688. https://doi.org/10.1542/neo.23-10-e677
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