Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome (Chapter 268)
Michael T. Brady, MD, Deborah Persaud, MD, William Moss, MD, MPH, 2016. "Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome (Chapter 268)", American Academy of Pediatrics Textbook of Pediatric Care, Thomas K. McInerny, MD, FAAP, Henry M. Adam, MD, FAAP, Deborah E. Campbell, MD, FAAP, Thomas G. DeWitt, MD, FAAP, Jane Meschan Foy, MD, FAAP, Deepak M. Kamat, MD, PhD, FAAP, Rebecca Baum, MD, FAAP, Kelly J. Kelleher, MD, MPH, FAAP
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Children who have acquired immunodeficiency syndrome (AIDS) were first identified in 1983, 2 years after the description of AIDS in adults.1 Subsequently it became clear that AIDS was a manifestation of advanced human immunodeficiency virus (HIV) infection. By the end of 2007, an estimated 4,000 children younger than 21 years were living with HIV infection in the United States.2 AIDS was the case definition used to describe the collection of opportunistic infections or cancers that were noted in HIV-infected individuals before it was known that HIV was the etiologic agent responsible for the predisposition to these opportunistic conditions....