Cannabis use has been evolving in both recreational drug use and medicinal uses, in part due to the recent introduction of various strains and components. With increasing use, we have seen emergence of a hyperemesis syndrome called cannabinoid hyperemesis syndrome characterized as intractable vomiting, nausea, and abdominal pain in the context of prolonged cannabinoid use. Although the antiemetic properties of cannabis have been known for years, the paradoxical effect of hyperemesis has yet to be elucidated. Herein we discuss the current research, epidemiology, and diagnosis and treatment of cannabinoid hyperemesis syndrome. Without timely diagnosis and treatment, patients may experience significant physical and emotional distress, as well as place unnecessary financial burden on the medical system.
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September 2021
Articles|
September 01 2021
Cannabinoid Hyperemesis Syndrome in Pediatrics: An Emerging Problem
Kaushal Dosani, MD;
Kaushal Dosani, MD
*University of Nevada Las Vegas School of Medicine, Las Vegas, NV
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Carolina Koletic, MD;
Carolina Koletic, MD
*University of Nevada Las Vegas School of Medicine, Las Vegas, NV
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Rabea Alhosh, MD
Rabea Alhosh, MD
*University of Nevada Las Vegas School of Medicine, Las Vegas, NV
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AUTHOR DISCLOSURE
Drs Dosani, Koletic, and Alhosh have disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/investigative use of a commercial product/device.
Pediatr Rev (2021) 42 (9): 500–506.
Citation
Kaushal Dosani, Carolina Koletic, Rabea Alhosh; Cannabinoid Hyperemesis Syndrome in Pediatrics: An Emerging Problem. Pediatr Rev September 2021; 42 (9): 500–506. https://doi.org/10.1542/pir.2019-0097
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