Immunization in Children With a Personal or Family History of Seizures
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Published:2021
2021. "Immunization in Children With a Personal or Family History of Seizures", Red Book: 2021–2024 Report of the Committee on Infectious Diseases, Committee on Infectious Diseases, American Academy of Pediatrics, David W. Kimberlin, MD, FAAP, Elizabeth D. Barnett, MD, FAAP, Ruth Lynfield, MD, FAAP, Mark H. Sawyer, MD, FAAP
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Studies have demonstrated a short-term increased risk of a febrile seizure (ie, generalized, brief, self-limited seizure) following receipt of several vaccines (eg, diphtheria and tetanus toxoids and whole-cell pertussis vaccine [DTwP]; measles, mumps, and rubella vaccine [MMR]; measles, mumps, rubella, and varicella vaccine [MMRV]; and 13-valent pneumococcal conjugate vaccine [PCV13] and influenza vaccine). Infants and children with a personal or family history of seizures of any etiology might be at greater risk of having a febrile seizure after receipt of these vaccines compared with children without such histories. No evidence indicates that febrile seizures cause permanent brain damage or epilepsy,...