Arboviruses (also see Chikungunya, p 254, Dengue, p 301, West Nile Virus, p 848, and Zika Virus, p 854)
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Published:2021
2021. "Arboviruses (also see Chikungunya, p 254, Dengue, p 301, West Nile Virus, p 848, and Zika Virus, p 854)", Red Book: 2021–2024 Report of the Committee on Infectious Diseases, Committee on Infectious Diseases, American Academy of Pediatrics, David W. Kimberlin, MD, FAAP, Elizabeth D. Barnett, MD, FAAP, Ruth Lynfield, MD, FAAP, Mark H. Sawyer, MD, FAAP
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Most infections with arthropodborne viruses (arboviruses) are subclinical. Symptomatic illness usually manifests as 1 of 3 primary clinical syndromes: generalized febrile illness, neuroinvasive disease, or hemorrhagic fever (Table 3.1).
Arboviruses are RNA viruses that are transmitted to humans primarily through bites of infected arthropods (mosquitoes, ticks, sand flies, and biting midges). More than 100 arboviruses are known to cause human disease. The viral families responsible for most arboviral infections in humans are Flaviviridae (genus Flavivirus), Togaviridae (genus Alphavirus), Peribunyaviridae (genus Orthobunyavirus), and Phenuiviridae (genus Phlebovirus). Reoviridae (genus Coltivirus) also are responsible for...