Human Papillomaviruses
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Published:2021
2021. "Human Papillomaviruses", Red Book: 2021–2024 Report of the Committee on Infectious Diseases, Committee on Infectious Diseases, American Academy of Pediatrics, David W. Kimberlin, MD, FAAP, Elizabeth D. Barnett, MD, FAAP, Ruth Lynfield, MD, FAAP, Mark H. Sawyer, MD, FAAP
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Most human papillomavirus (HPV) infections are subclinical, and 90% resolve spontaneously within 2 years. However, persistent HPV infection can cause benign epithelial proliferation (warts) of the skin and mucous membranes as well as cancers of the lower anogenital tract and the oropharynx. HPVs can be grouped into cutaneous and mucosal types. The cutaneous types cause common skin warts, plantar warts, flat warts, and thread-like (filiform) warts. These cutaneous warts are benign. Certain mucosal types (low risk) are associated with warts or papillomas of mucous membranes, including the upper respiratory tract and anogenital, oral, nasal, and conjunctival areas. Other mucosal types...