Antimicrobial Prophylaxis
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Published:2021
2021. "Antimicrobial Prophylaxis", Red Book: 2021–2024 Report of the Committee on Infectious Diseases, Committee on Infectious Diseases, American Academy of Pediatrics, David W. Kimberlin, MD, FAAP, Elizabeth D. Barnett, MD, FAAP, Ruth Lynfield, MD, FAAP, Mark H. Sawyer, MD, FAAP
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Antimicrobial prophylaxis is defined as the use of antimicrobial drugs in the absence of suspected or documented infection to prevent development of infection or disease and is a common practice in pediatrics. Although the efficacy of antimicrobial prophylaxis has been demonstrated for some conditions, this is not the case for many more conditions for which it is nevertheless used. Concerns about the emergence of resistant bacterial pathogens has led to a reexamination of the role of antimicrobial prophylaxis, especially for conditions for which prolonged administration is required, such as prevention of recurrent otitis media (OM) and urinary tract infection (UTI)....