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Key Action Statement Profile: KAS 4B

Aggregate evidence quality Grade C 
Benefits Successful treatment of β-lactamase–producing organisms. 
Risks, harms, cost Cost of antibiotic. Increased adverse effects. 
Benefits-harms assessment Preponderance of benefit. 
Value judgments Efficacy is more important than taste. 
Intentional vagueness None. 
Role of patient preferences Concern regarding side effects and taste. 
Exclusions Patients with known penicillin allergy. 
Strength Recommendation 
Aggregate evidence quality Grade C 
Benefits Successful treatment of β-lactamase–producing organisms. 
Risks, harms, cost Cost of antibiotic. Increased adverse effects. 
Benefits-harms assessment Preponderance of benefit. 
Value judgments Efficacy is more important than taste. 
Intentional vagueness None. 
Role of patient preferences Concern regarding side effects and taste. 
Exclusions Patients with known penicillin allergy. 
Strength Recommendation 
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