American Academy of Pediatrics

Aggregate evidence quality: B; randomized controlled trials with limitations.
Benefit	Increase clinical cures, shorten illness duration, and may prevent suppurative complications in a high-risk patient population.
Harm	Adverse effects of antibiotics.
Cost	Direct cost of therapy.
Benefits-harm assessment	Preponderance of benefit.
Value judgments	Concern for morbidity and possible complications if untreated.
Role of patient preference	Limited.
Intentional vagueness	None.
Exclusions	None.
Strength	Strong recommendation.

Aggregate evidence quality: B; randomized controlled trials with limitations.
Benefit	Increase clinical cures, shorten illness duration, and may prevent suppurative complications in a high-risk patient population.
Harm	Adverse effects of antibiotics.
Cost	Direct cost of therapy.
Benefits-harm assessment	Preponderance of benefit.
Value judgments	Concern for morbidity and possible complications if untreated.
Role of patient preference	Limited.
Intentional vagueness	None.
Exclusions	None.
Strength	Strong recommendation.