Histopathology of case 1. A–C, Hematoxylin and eosin staining. D–F, Anti-RSV immunostaining (Chemicon, Temecula, CA). G, Immunostaining for Glial fibrillary acidic protein (GFAP). Scale bar, 50 μm. A, Bronchiolitis is accompanied by lymphocytes. The lumen is obstructed by peeled epithelia and mucosal fluid with some macrophages. B, Mild pneumonia is accompanied by neutrophils, lymphocytes, and macrophages. C, Extravasation of plasma is observed around intracerebral arteries. D, Peeled bronchial epithelia and macrophages are RSV positive. E, Most of the alveolar epithelial cells are RSV negative. F, The brain parenchyma and perivascular edema are RSV negative. G, The number and structure of astroglia are preserved.